Professor Robert Medcalf was awarded his Ph.D. from the University of Melbourne in 1984. His first post-doctoral appointment was at the University of Melbourne where he investigated the role of the plasminogen activating system in rheumatoid arthritis. In 1986, he continued his research in Lausanne, Switzerland where he extended his interest in the transcriptional regulation of the plasminogen activators and their inhibitors. In 1993, he returned to Australia where he established a laboratory in the Department of Medicine at Monash University in Melbourne and was a foundation member of the Australian Centre for Blood Diseases (ACBD). During this time he initiated a program of research investigating the role of the fibrinolytic system in the central nervous system and this is currently the most prominent research focus of his laboratory. He has a particular interest in understanding how the fibrinolytic protease, tissue type plasminogen activator (t-PA) potentiates neuronal injury and modulates blood brain barrier permeability and the influence of this in ischaemic stroke. His laboratory is also exploring the role of the fibrinolytic system in traumatic brain injury and in models of neurogeneration. He has published more than 110 papers in peer reviewed journals. He was appointed to the NHMRC Fellowship Scheme in 2003 (SRF-A) and was promoted to the level of Principle Research Fellow in 2012.
Australian Centre for Blood Diseases – Monash University
Tel: (03) 9903 0133
Fax: (03) 9903 0228